| 論文名 |
Regenerative electronic biosensors using supramolecular approaches. |
| 著者 |
Xuexin Duan
Nitin K Rajan
David A Routenberg
Jurriaan Huskens
Mark A Reed
|
| キーワード |
|
| 出版年月 |
1970年1月 |
| 発表先 |
ACS Nano. 2013 May 28;7(5):4014-21. |
| WEBサイト |
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| 論文概要（和文） |
超分子アプローチを使用した再生電子バイオセンサー。 |
| 論文概要（英文） |
A supramolecular interface for Si nanowire FETs has been developed with the aim of creating regenerative electronic biosensors. The key to the approach is Si-NWs functionalized with β-cyclodextrin (β-CD), to which receptor moieties can be attached with an orthogonal supramolecular linker. Here we demonstrate full recycling using the strongest biomolecular system known, streptavidin (SAv)-biotin. The bound SAv and the linkers can be selectively removed from the surface through competitive desorption with concentrated β-CD, regenerating the sensor for repeated use. An added advantage of β-CD is the possibility of stereoselective sensors, and we demonstrate here the ability to quantify the enantiomeric composition of chiral targets. |
