| 論文名 |
Advances in enantiomeric resolution on monolithic chiral stationary phases in liquid chromatography and electrochromatography. |
| 著者 |
Zeid A Al-Othman
Abdulrahman Al-Warthan
Imran Ali
|
| キーワード |
|
| 出版年月 |
1970年1月 |
| 発表先 |
J Sep Sci. 2014 May;37(9-10):1033-57. doi: 10.1002/jssc.201301326. Epub 2014 Apr 11. |
| WEBサイト |
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| 論文概要（和文） |
液体クロマトグラフィーおよびエレクトロクロマトグラフィーにおけるモノリシックキラル固定相の鏡像異性体分離の進歩 |
| 論文概要（英文） |
During the last decade, chiral monolithic stationary phases have been prepared and used for rapid enantioseparations in CEC and HPLC. Various chiral selectors are used to prepare these CSPs. The preparation, properties, and applications of these CSPs are discussed in this paper. Attempts have been made to describe optimization strategies and the chiral recognition mechanisms. A comparison of chiral separations in CEC and HPLC is described. Efforts have also been made to predict the future perspectives and challenges of chiral monolithic stationary phases. The most effective chiral selectors include polysaccharides, cyclodextrins, and macrocyclic glycopeptide antibiotics. These chiral phases produced acceptable analytical enantiomeric separation of a variety of racemates. However, the development of these CSPs for preparative-scale separations is needed. |
