| 論文名 |
An upconversion nanocomposite for fluorescence resonance energy transfer based cholesterol-sensing in human serum. |
| 著者 |
Yujie Ding
Hao Zhu
Xiaoxia Zhang
Jiangang Gao
E S Abdel-Halim
Liping Jiang
Jun-Jie Zhu
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| キーワード |
|
| 出版年月 |
1970年1月 |
| 発表先 |
Nanoscale. 2014 Dec 21;6(24):14792-8. doi: 10.1039/c4nr04380d. Epub 2014 Oct 31. |
| WEBサイト |
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| 論文概要（和文） |
ヒト血清における蛍光共鳴エネルギー移動に基づくコレステロール感知のためのアップコンバージョンナノコンポジット |
| 論文概要（英文） |
Upconversion nanophosphors (UCNPs) are extremely useful for analytical applications, since they display a high signal-to-noise ratio, and their photobleaching can be ignored. Herein, a novel upconversion nanocomposite composed of β-cyclodextrin (β-CD) derivative modified UCNPs and rhodamine B (RB) was prepared for the detection of cholesterol (Cho). The upconversion luminescence (UCL) emission can serve as a Cho-sensing signal by an effective fluorescence resonance energy transfer (FRET) process, using UCNPs as the donor and RB as the quencher. The sensor for Cho detection in human serum shows excellent sensitivity and selectivity, which has the potential for clinical applications in the analysis of other biological and environmental samples. |
