| 論文名 |
[A case of rocuronium-induced anaphylactic shock successfully treated with sugammadex]. |
| 著者 |
Tomoki Ishikawa
Naoya Kawanoue
Eriko Minami
Etsu Iwasaki
Mizue Ishii
Hiroyuki Kobayashi
Satoru Oku
Takeshi Mikane
Hiroaki Tokioka
Keiko Kanazawa
|
| キーワード |
|
| 出版年月 |
1970年1月 |
| 発表先 |
Masui. 2013 Oct;62(10):1230-2. |
| WEBサイト |
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| 論文概要（和文） |
[スガマデクスによる治療が成功したロクロニウム誘発アナフィラキシーショックの症例]。 |
| 論文概要（英文） |
We report a case of a 19-year-old male with rocuronium-induced anaphylactic shock. He was scheduled for endoscopic sinus surgery for chronic sinusitis under general anesthesia. Induction of anesthesia was done with fentanyl, propofol and sevoflurane. Just after administration of rocuronium, he developed tachycardia with extended exanthema on the face, anterior chest wall and abdomen. He was difficult to ventilate manually with mask and then intubated without difficulty. The carotid arterial pulse was not palpable and adrenaline was given intermittently to maintain blood pressure. Although the systolic blood pressure increased to 80 mmHg, hemodynamics was unstable with adrenaline. Sugammadex was then given and the blood pressure became stable without adrenaline. Exanthema also disappeared gradually. He was then transferred to ICU and extubated without any sequela. The plasma beta-tryptase increased to 46 microg x l(-1) during the shock state and returned to 14.1 microg x l(-1) 8 hrs after the event. The blood hemoglobin level also increased to 21.3 g x dl(-1) during the shock state and returned to 17.2 g x dl(-1) during the recovery phase. The laboratory data showed a marked increase in vascular permeability caused by rocuronium-induced anaphylactic shock. |
