| 論文名 |
Chiral recognition and kinetic resolution of aromatic amines via supramolecular chiral nanocapsules in nonpolar solvents. |
| 著者 |
Toshiyuki Kida
Takuya Iwamoto
Haruyasu Asahara
Tomoaki Hinoue
Mitsuru Akashi
|
| キーワード |
|
| 出版年月 |
1970年1月 |
| 発表先 |
J Am Chem Soc. 2013 Mar 6;135(9):3371-4. |
| WEBサイト |
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| 論文概要（和文） |
非極性溶媒中での超分子キラルナノカプセルを介した芳香族アミンのキラル認識と速度論的分割。 |
| 論文概要（英文） |
Herein we report the first example of chiral recognition and kinetic resolution of aromatic amine guests using supramolecular nanocapsules assembled from cyclodextrin derivatives in nonpolar media. With these nanocapsules, an extremely high chiral recognition of 1-(1-naphthyl)ethylamine (1) in cyclohexane was achieved, with a binding selectivity of up to 41 for (S)-1 over (R)-1. In addition, kinetic resolution of 1 through enantioselective N-acylation was accomplished with an enantiomeric excess of up to 91%. |
