| 論文名 |
Complete sets of monosubstituted γ-cyclodextrins as precursors for further synthesis. |
| 著者 |
Mark?ta Bl?hov?
Eva Bedn??ov?
Michal ?ezanka
Jind?ich Jind?ich
|
| キーワード |
|
| 出版年月 |
1970年1月 |
| 発表先 |
J Org Chem. 2013 Jan 18;78(2):697-701. |
| WEBサイト |
|
| 論文概要（和文） |
さらなる合成のための前駆体としての一置換γ-シクロデキストリンの完全なセット。 |
| 論文概要（英文） |
Regioselective alkylation of γ-cyclodextrin with allyl or propargyl bromide, using optimized reaction conditions, followed by peracetylation of the remaining hydroxyl groups and separation of isomers resulted in the set of peracetylated 2(I)-O-, 3(I)-O- and 6(I)-O-alkylated cyclodextrins in up to 19% yields. Ozonolysis or oxidative cleavage of peracetylated allyl derivatives resulted in a complete set of peracetylated 2(I)-O-, 3(I)-O-, and 6(I)-O-formylmethyl or -carboxymethyl derivatives. All of these derivatives are useful precursors for further preparation of regioselectively monosubstituted derivatives of γ-cyclodextrin. |
