| 論文名 |
Cyclodextrin-Based Ionic Liquids as Enantioselective Stationary Phases in Gas Chromatography. |
| 著者 |
Nuno Costa
Sara Matos
Marco D R Gomes da Silva
M Manuela A Pereira
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| キーワード |
|
| 出版年月 |
1970年1月 |
| 発表先 |
Chempluschem. 2013 Dec;78(12):1466-1474. |
| WEBサイト |
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| 論文概要（和文） |
ガスクロマトグラフィーにおけるエナンチオ選択的固定相としてのシクロデキストリンベースのイオン液体。 |
| 論文概要（英文） |
New permethylated mono-6-deoxy-6-pyridin-1-ium and mono-6-deoxy-6-(1-vinyl-1H-imidazol-3-ium)-α- and -β-cyclodextrin trifluoromethanesulfonate ionic liquids were synthesized from the corresponding permethylated mono-6-hydroxycyclodextrins in a one-pot reaction and solvent-free procedure. Regioselective transformation of native α- and β-cyclodextrins with the use of a bulky tert-butyldiphenylsilyl protecting group afforded the desired 6-monosubstituted permethylated cyclodextrin derivatives in moderate yields. The new ionic liquids were tested as stationary phases in capillary GC columns towards chiral discrimination in enantio-GC analysis of racemic mixtures. The permethylated 6-deoxy-6-pyridin-1-ium-α-cyclodextrin trifluoromethanesulfonate displayed good enantiomeric separations for some racemic esters and lactones, as well as epoxides. In particular, for both the racemic whiskey lactone and the high boiling point menthyl laurate, not successfully separated in a commercial cyclodextrin phase, the enantiomeric separations were achieved isothermally at 140 °C. |
