| 論文名 |
Host-guest chemistry of cyclodextrin carbamates and cellulose derivatives in aqueous solution. |
| 著者 |
Guo X
Jia X
Du J
Xiao L
Li F
Liao L
Liu L
|
| キーワード |
|
| 出版年月 |
1970年1月 |
| 発表先 |
Carbohydr Polym. 2013 Oct 15;98(1):982-7. |
| WEBサイト |
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| 論文概要(和文) |
水溶液中のシクロデキストリンカルバメートとセルロース誘導体のホスト-ゲスト化学。 |
| 論文概要(英文) |
Supramolecular polymer micelles were prepared on basis of the inclusion complexation between cyclodextrin carbamates and cellulose derivatives in aqueous media. Cyclodextrin carbamates were synthesized by microwave-assisted method from cyclodextrin and urea. The urea modified cyclodextrin shows the higher yield than the physical mixture of urea/cyclodextrin in the micellization with cellulose derivatives. The supramolecular structure of the core-shell micelles was demonstrated by (1)H NMR spectra, TEM images, and fluorescence spectra. The drug release behavior of the supramolecular polymer micelles was evaluated using prednisone acetate as a model drug. The drug loaded micelles showed steady and long time drug release behavior. With these properties, the supramolecular polymer micelles are attractive as drug carriers for pharmaceutical applications. |