| 論文名 |
Immobilisation of β-cyclodextrin on glass: characterisation and application for cholesterol reduction from milk. |
| 著者 |
Muhammad Nazir Tahir
Yan Lee
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| キーワード |
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| 出版年月 |
1970年1月 |
| 発表先 |
Food Chem. 2013 Aug 15;139(1-4):475-81. |
| WEBサイト |
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| 論文概要（和文） |
β-シクロデキストリンのガラス上への固定化：キャラクタリゼーションと牛乳からのコレステロール低減への応用。 |
| 論文概要（英文） |
β-Cyclodextrin (β-CD) was converted into β-CD-N3 by chemical modification and subsequently attached covalently on glass surface by click reaction. Functionalised glass surface was characterised by static water contact angle and X-ray photoelectron spectroscopy (XPS). Both techniques show that β-CD was successfully attached on glass surface. β-CD on solid surface was used to make a complexation with cholesterol to remove it from milk. 69±1% cholesterol was reduced in 4 h at 25°C and 170 rpm. The same surface was used repeatedly for eight cycles and it maintained its efficiency, with 68±2% cholesterol reduction. Modified glass surface showed almost no degradation as confirmed from XPS analysis after eight cycles of repeated use in cholesterol reduction experiments. The high efficiency and stability of functional monolayer was attributed to its specific structure with relatively low number of functional groups and longer spacer chain length to providing higher flexibility to β-CD molecules. |
