| 論文名 |
Isolation of Prunin from the fruit shell of Bixa orellana and the effect of β-cyclodextrin on its binding with calf thymus DNA. |
| 著者 |
Sameena Yousuf
N Sudha
G Murugesan
Israel V M V Enoch
|
| キーワード |
|
| 出版年月 |
1970年1月 |
| 発表先 |
Carbohydr Res. 2013 Jan 10;365:46-51. |
| WEBサイト |
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| 論文概要（和文） |
Bixa Orellanaの果実殻からのプルニンの単離および子牛胸腺DNAとの結合に対するβ-シクロデキストリンの影響。 |
| 論文概要（英文） |
Naringenin-7-O-glucoside [Prunin (Pru)] was isolated from the fruit shell of Bixa orellana L. The binding of Pru with calf thymus DNA (ctDNA) and the influence of cyclomaltoheptaose (β-cyclodextrin, β-CD) on the binding were studied by absorption and fluorescence spectroscopic techniques. The comparison of the binding modes of Pru/β-CD and ctDNA-Pru/β-CD suggested that β-CD extracted Pru from DNA for forming inclusion complex. Molecular modeling gave added support to the above results. Fluorescence microscopy was used to visualize the effect of β-CD on the bindings. |
