| 論文概要（英文） |
Lycopene, which is a functional ingredient in tomato and watermelon, is known to have a powerful antioxidant effect and prevent various lifestyle-related diseases. In addition to lycopene, tomato also contains 13-oxo-9, 11-octadecadienoic acid (13-oxo-ODA), which has a fat burning effect. Thus, tomato is an attractive vegetable having some effective ingredients for health. But lycopene has some unfavorable characteristics like easily oxidizable, low water solubility and therefore low absorbability. We have found that ingestion of fat-soluble substance-γ-cyclodextrin (γ-CD) inclusion complex gives the absorption improvement of the fat-soluble substance. It is due to the formation of molecular bile acid micelle of the fat-soluble substance after releasing from γ-CD. Therefore, in this study, for the purpose of improving the oral absorbability of lycopene in tomato, we prepared tomato CD powders and evaluated the solubility of lycopene in artificial intestinal fluid, which can be used as an index of absorbability. |
