| 論文名 |
Molecularly imprinted photonic polymer based on β-cyclodextrin for amino acid sensing. |
| 著者 |
Xiao-Yan Liu
Hong-Xun Fang
Li-Ping Yu
|
| キーワード |
|
| 出版年月 |
1970年1月 |
| 発表先 |
Talanta. 2013 Nov 15;116:283-9. |
| WEBサイト |
|
| 論文概要（和文） |
分子認識：シクロデキストリン水溶液中の巨視的高分子ゲルの膨潤度に対するパラ対金属置換フェニル部分の影響。 |
| 論文概要（英文） |
A novel molecularly imprinted photonic polymer (MIPP) using maleic anhydride modified β-cyclodextrin (β-CD) and acrylic acid as functional monomers has been presented for amino acid sensing. Reactive β-CD monomer carrying vinyl carboxylic acid functional groups was first synthesized. MIPP was fabricated by filling precursor solution into the interstitial spaces of polystyrene photonic crystal templates, followed by a thermal polymerization at 55 °C. Characterization showed that the MIPP possessed an opal photonic crystal structure. This β-CD-based MIPP could undergo a swelling change from 590 nm to 704 nm and still retain the molecular imprinting recognition ability during the sensing of L-phenylalanine (L-Phe). A function relationship was found between the diffraction wavelength shift and the logarithm of L-Phe concentration in the range of 10(-8)M to 10(-4)M at pH 6. A wavelength shift of 114 nm for L-Phe was observed within 30s, whereas there were no obvious shifts for d-Phe, L-tyrosine and L-tryptophan, indicating that the β-CD-based MIPP had high specificity and rapid response to L-Phe. The developed MIPP sensor has been applied to detect L-Phe in compound amino acid injection sample. |
